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A decline in stress-induced uptake of serotonin in the hippocampus and prefrontal cortex of mice carrying APOE4 relative to APOE3 is associated with an increase in stress-induced depressive-like behavior (Fang et al., 2021)

Follow the discussion The FDA's Pharmacy Compounding Advisory Committee (PCAC) will meet July 2324, 2026, and the sessions will be available to the public via live webcast

Investigating how this local metabolic machinery is regulated, potentially by activity-induced calcium signals, may reveal why synapses exhibit varying vulnerabilities to energy stress in neurodegenerative diseases