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The tripeptide H-Gly-His-Lys-OH (GHK) (Product: 4000308 Liver Cell Growth Factor) was originally identified in human plasma and has a high affinity for copper2+ (Cu2+)

To determine if protein UFMylation regulated ferroptosis, we treated cells with RSL3 and Erastin in the presence of DKM 2-93 and found that DKM 2-93 also heightened sensitivity to these ferroptosis inducers in HepG2 cells (Figs

Free Radic Biol Med 94:230242 di Maio R, Mastroberardino PG, Hu X et al (2011) Pilocapine alters NMDA receptor expression and function in hippocampal neurons: NADPH oxidase and ERK1/2 mechanisms [J]

Harris and his multidisciplinary team remain committed to translating these insights from the laboratory bench to clinical application, aiming to develop targeted therapies that impair tumor metabolism while preserving normal tissue function, ultimately improving survival rates and quality of life for cancer patients