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Description

Thyroid hormone upregulates Cav1.2 channels in cardiac cells via the downregulation of the channels' 4 subunit

in rats

Studies show that mTOR can exacerbate pyroptosis of CD4 + T cells by negatively regulating the PPAR-Nrf2 signaling pathway, promoting the occurrence of sepsis-related immune suppression and ultimately resulting in poor clinical prognosis (54)