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10.1371/journal.pone.0116879 238 ZhangM.PanH.XuY.WangX.QiuZ.JiangL

The increase was even greater for specific products

Mechanistic studies have reported AMY receptor subtype dependence for the body weight effect in model systems, supporting receptor anchored interpretation

In addition, early-phase clinical trials focused on MDSC-targeted therapies, especially those incorporating advanced delivery systems like nanoparticles or exosomes should be prioritized, moreover, integration of systems biology and artificial intelligence can provide predictive models for therapy optimization, further advancing the field of MDSC-targeted immunotherapy