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Procalcitonin (PCT) the biomarker of choice to aid in the diagnosis of sepsis Procalcitonin is regarded as a biomarker with both diagnostic and prognostic impact, offering Emergency Departments and Intensive Care clinicians a key tool to aid in the diagnosis of sepsis, and thereby improve antibiotic decision-making and potentially improve clinical outcomes [1] Procalcitonin (PCT), a 116amino acid polypeptide prohormone of calcitonin, has emerged as a biomarker to aid in the diagnosis of sepsis and with a high potential to improve the clinical assessment of patients [1]

Medical necessity documentation prevents these denials

This can affect the arm, hand, leg, foot, and sometimes the face on the same side

The main reason: the lack of randomized controlled clinical trials in humans