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Patent 11,332,463 Crowley BM, Bell IM, Harvey AJ, Shipe WD, Leavitt KJ, Sanders JM, Guiadeen, DG , Suen LM , Greshock TJ, Rada VL (2020) Substituted bicyclic heteroaryl allosteric modulators of nicotinic acetylcholine receptors

Brown JWP, Buell AK, Michaels TCT, Meisl G, Carozza J, Flagmeier P, Vendruscolo M, Knowles TPJ, Dobson CM, Galvagnion C

The MSSG therefore recommends that healthcare professionals prescribe these medicines in line with their authorised use(s) only, taking into account guidance issued by national authorities or applicable national therapeutic guidelines

FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c