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IFN- 8 and IFN-stimulated gene expression 11 colocalize with HLA-I hyper-expression, which is a histopathological hallmark of T1D in insulin (INS)-containing islets 12

Application Areas: Metabolic Disease Research: Obesity, insulin resistance, type 2 diabetes mechanism and drug development Aging and Longevity Research: NAD+ homeostasis, mitochondrial function, regulation of cell aging pathways Neuroscience Research: Exploration of protective effects on neurodegenerative diseases such as Parkinsons disease Sports Science: Enhancing endurance, promoting muscle repair and improving physical performance research