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10.1038/nrm.2016.108 Nat Rev Mol Cell Biol

Infection 53 (4), 14131423

When wildtype and AQP4-deficient mice were given a low dose of the chemoconvulsant pentylenetetrazol (PTZ), it was observed that all wildtype mice exhibited seizure activity, whereas most of the AQP4-deficient mice did not produce any seizure activity (Binder et al., 2004)