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[153] There is evidence that for elderly people, physicians often repeatedly prescribe and administer cyanocobalamin injections inappropriately, evidenced by the majority of subjects in one large study either having had normal serum concentrations or having not been tested before the injections

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Ethics All animal experiments followed the animal ethics guidelines and were approved by the Yonsei University Institutional Animal Care and Use Committee, Yonsei University School of Medicine (Seoul, Korea)