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In patients with newly diagnosed Types I and II diabetes, where some islet cell function remains, the polynucleotides or polypeptides, and/or agonists or antagonists of the invention, could be used to maintain the islet function so as to alleviate, delay or prevent permanent manifestation of the disease

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Ribeiro et al., 2012), which plays a critical role in GSH regeneration: GR catalyzes the generation of GSH from GSSG through an NADPH-dependent mechanism

doi: 10.1210/jc.2016-2692 148 HuangRXueXLiSWangYSunYLiuWet al