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Liu H, Chen Z, Weng X, Chen H, Du Y, Diao C, et al

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In patients with concomitant coronary artery disease and type 2 diabetes, elevated TRPV1 expression in peripheral blood mononuclear cells correlates with increased circulating pro-inflammatory cytokines, including TNF-, IL-6, and monocyte chemoattractant protein-1 (MCP-1), and independently predicts future major adverse cardiovascular events (98)

To maintain the results, sunscreen should be applied after treatment, and not direct exposure to sunlight