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We allowed these models to mature for two (BT474-R) or three (BT474) weeks before performing treatment with TZ, T-DM1 or T-DXd for an additional week (Fig

doi: 10.1073/pnas.011513098 204 OConnorTGWinterMAHunnJCarnahanJPressmanEKGloverVet al

Moreover, One mechanism through which RNS contributes to IBD pathology is the formation of Peroxynitrite(ONOO-), a highly reactive oxidant formed by the reaction of NO with O2 (148)