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In LSS, the expression of the E3 ubiquitin ligase Smurf1 is markedly elevated, which promotes fibrosis and oxidative stress in LF cells, contributing to the progression of LSS by facilitating the ubiquitination and degradation of NRF2 [112]

We chose the conserved histidine catabolism pathway as a model to further elucidate this mechanism of SKN-1 activation, as histidine is an essential amino acid and its metabolic pathway remains largely uncharacterized in C

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118-120 Vestibular evoked myogenic potentials are electrical signals that can be measured in the neck or eye muscles and may provide valuable diagnostic information about the function of the vestibular system