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* Correspondence: Feng Luo, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Genome-wide CRISPR/Cas9 screen: Palbociclib sensitization and resistance A doxycycline-inducible Cas9-expressing MCF-7 iCas9 clone was generated by transduction of MCF-7 cells with the Edit-R Inducible Lentiviral hEF1a-Blast-Cas9 Nuclease (Dharmacon) and selected in 10 g/ml blasticidin for 5 days (MCF-7iCas9)