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It is apparent that crosstalk is essential for maintaining the delicate balance between CI/RI and various pathological processes, but it also increases the difficulty of precision treatment to a considerable extent

doi: 10.3389/fphar.2014.00196 Received 05 July 2014 Accepted 06 August 2014 Published 26 August 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Anastassios Papageorgiou, University of Turku, Finland

After an initial 3-4 treatments, most patients return for touch-up appointments on a regular schedule recommended by our experts