Mechanically, HDAC9 promotes the occurrence of tubulointerstitial fibrosis by deacetylating STAT1 and promoting its reactivation, resulting in G2/M phase arrest in RTECs
Schermer and colleagues aimed to investigate whether treatment with inhaled corticosteroid (fluticasone propionate) or oral NAC are effective in primary care patients

Disclosures: Max Schechter: Nothing to Disclose, Katherine Ni: Nothing to Disclose, Zoe Verzani: Nothing to Disclose, Kimberline Chew: Nothing to Disclose, Jang Hyun Kim: Nothing to Disclose, Lewis Paulino: Nothing to Disclose, Danielle Garfunkel: Nothing to Disclose, Lital Aliasi-Sinai: Nothing to Disclose, Daniel Alvarez: Nothing to Disclose, Adejoke Johnson: Nothing to Disclose, Soaptarshi Paul: Nothing to Disclose, Hamza Sadhra: Nothing to Disclose, Clara Tow: Nothing to Disclose, Don Rockey: WL Gore and Associates: Consultant, Cook Medical: Consultant, BD Medical: Consultant, AstraZeneca: Grant/Research Support, Direct: Grant/Research Support, Bio89: Grant/Research Support, Boehringer Ingelheim: Grant/Research Support, Durect: Grant/Research Support, Gilead: Grant/Research Support, Ipsen: Grant/Research Support, Intercept: Grant/Research Support, Inventiva: Grant/Research Support, Madrigal: Grant/Research Support, Ocelot: Grant/Research Support, Salix: Grant/Research Support, Novonordisk: Grant/Research Support, Galectin: Grant/Research Support, Versantis: Grant/Research Support, Viking: Grant/Research Support 1674 EARLY PALLIATIVE CARE (PC) IN END-STAGE LIVER DISEASE (ESLD) PATIENTS SIGNIFICANTLY IMPROVES HEALTH-RELATED QUALITY OF LIFE (HRQOL) Shirley Bong 1 Calvin Koh 1 Jonathan Lee 1 Mark Muthiah 1 Guan Huei Lee 1 Lin Liu 2 Yin Mei Lee 1 , 1 National University Hospital, 2 National University Singapore Background: ESLD is characterized by recurrent complications and repeated visits to the emergency room (ER) and hospital admissions

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