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Using a systems-based approach, we show that the amount of activated PKC affects cellular PKC levels

This may lead to: Brain fog Anxiety and irritability Mental fatigue Poor memory and focus Trouble sleeping One study showed that people with relatively more glutamine than glutamate in the brains motivation center had better stamina, less fatigue, and lower perceived effort during demanding tasks 8

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It has been proven that MSG causes Central Nervous System (CNS) nerve cell destruction in hypothalamus and pituitary gland, which can affect Gonadotropin-Releasing Hormone (GnRH) secretion [51,52,53,54]