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A clinically useful claim requires patient-relevant outcomes, appropriate controls and a favourable benefit-to-risk assessment

doi: 10.1016/j.toxicon.2021.09.002 Nixon, Samantha A., Robinson, Samuel D., Agwa, Akello J., Walker, Andrew A., Choudhary, Shivani, Touchard, Axel, Undheim, Eivind A.B., Robertson, Alan, Vetter, Irina, Schroeder, Christina I., Kotze, Andrew C., Herzig, Volker and King, Glenn F

Important considerations for implanted drug delivery systems include the prevention of drug leakage, the size of the implant device, and methods for removal once the device has reached the end of its use