glutathione-responsive prodrug

glutathione-responsive prodrug Preparation and Characterization of a Doxorubicin Modified by 2-Nitrobenzenesulfonamide Group—Its Selective Cytotoxicity Toward Cells with Enhanced Glutathione Production Engineering glutathione-responsive near-infrared polymeric prodrug

Name: glutathione-responsive prodrug Preparation and Characterization of a Doxorubicin Modified by 2-Nitrobenzenesulfonamide Group—Its Selective Cytotoxicity Toward Cells with Enhanced Glutathione Production Engineering glutathione-responsive near-infrared polymeric prodrug
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Engineering glutathione responsive near infrared polymeric prodrug system for fluorescence imaging in tumor therapy ScienceDirect Nanomedicines with Versatile GSH Responsive Linkers for Cancer Theranostics ACS Biomaterials Science & Engineering Glutathionetriggered prodrugs: Design strategies, potential applications, and perspectives Zhao 2024 Medicinal Research Reviews Wiley Online Library Synthesis of glutathione responsive, amphiphilic methotrexate based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer ScienceDirect

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Description

disrupt hormones and immune signaling via AHR pathways PCBs - historically used industrially

Ramanathan, S

These results indicate that the loss of cellular glutathione and increase in oxidative stress alters vitamin D metabolism genes and vitamin D receptors, which can predispose the body to 25(OH)VD 3 deficiency