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SKU: 5952751850
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Da Silva, J.S

Pharmacologic inhibition of SIRT2 enhanced antitumor immunity by promoting metabolic reprogramming toward a profound hyper-metabolic state with enhanced capacity for aerobic glycolysis in tumor-infiltrating T cells [133]

Uranova NA, Casanova MF, DeVaughn NM, Orlovskaya DD, Denisov DV

DBA analysis revealed significant gain of the active transcription mark H3K27Ac at the TFAM promoter in MEC-1/N M cells compared to MEC-1/N WT (logFC = 0.47, FDR = 0.007), with no differential enrichment for the repressive histone mark H3K27me3 (Fig