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164 Mesenchymal stem cell (MSC)-derived exosomes represent the most extensively utilized vehicles for intranasal-to-brain drug delivery, demonstrating therapeutic efficacy across multiple neurological disorders including AD, Parkinsons disease, epilepsy, depression, and traumatic brain injury

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Rb1 also protected the intestinal barrier and downregulated the oxidative stress response, thereby regulating the structure of the intestinal flora and the profile of intestinal fatty acids