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Then the NICE guidance say (as arbitrary it is on many areas e.g treatment frequency) says: "Maintenance treatment with hydroxocobalamin 1 mg intramuscularly every 3 months for life where B12 deficiency is not thought to be diet related

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Other COPD intervention studies are underway to examine the effect(s) of 3,000 6,000 IU of vitamin D3 on rehabilitation (NCT01416701), as well as time to first upper respiratory infection and first moderate-to-severe exacerbation (NCT00977873) (clinicaltrials.gov 2012)

American Academy of Clinical Toxicology (February 2013), "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation , American College of Medical Toxicology and American Academy of Clinical Toxicology, retrieved 5 December 2013 David Rakel, Integrative Medicine 5th edition, Elsevier, 2023