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For that group, treating the deficiency is important, because an untreated deficiency does not stay still

Even so, these delivery platforms offer a promising strategy to enhance the therapeutic efficacy of apigenin and ellagic acid in PCOS and related comorbidities

In vivo , apigenin reduces the secretion of pro-inflammatory factors (IL-1, IL-6, and TNF-), reduces the expression of the DCs costimulatory molecules CXCR4 and MHCII, and reduces the number of Langerhans cells

Research has explored possible effects on neuronal signaling, oxidative stress, seizures, and neuroprotection, but no large human trials have demonstrated reliable improvements in memory, cognition, or neurological performance