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Zara, Janelle

If youve had too much to drink, it can be difficult to deal with the hangover

Moreover, the biliary secretion of NO species was significantly diminished in UDCA-infused transport mutant [ATPbinding cassette C2/multidrug resistanceassociated protein 2deficient] rats, and this finding was consistent with the involvement of the glutathione carrier ABCC2/Mrp2 in the canalicular transport of GSNO

Subsequent reporter assays supported this, showing decreased activity of CAV2 promoter upon PPAR overexpression in 293T cells, confirming that PPAR could inhibit the transcription of CAV2 in normal cells (Fig