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58 In a pilot trial in patients with diabetes, vascular function in response to acute (2 h after 24 g of oral erythritol) and chronic (36 g/d over 4 weeks) erythritol consumption was examined

Furthermore, upregulation of IL-6 and TNF- may enhance a pro-coagulant state by inducing TF expression in VEC, thereby contributing to the development of DVT [38, 39]

Thus, this competition may reflect a naturally evolved mechanism to efficiently co-regulate inflammatory versus anti-inflammatory pathways, fine-tuning the extent of an inflammatory response

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