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Padma-Nathan, H

But at the same time and in the same lobule there may be cells with lesser injury, on the path to necrosis, but with hepatocytes that can be salvaged through interruption of the cycle of continued JNK activation and oxidative/nitrosative stress

Timely self-elimination of damaged mitochondria from cells through mitophagy is an important quality control mechanism for cell homeostasis and survival during injury and repair [42]