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and the scopolamine Dihexa group = 115.2 s

Dihexa is not a conventional peptide but a peptidomimetic a small molecule (~504 Da) designed to mimic peptide binding activity while resisting enzymatic degradation

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In contrast, substitution to an amidated proline instead of an amidated tyrosine in the C-terminus of rAmy is well tolerated, resulting in enhanced affinity and activity at both the CTR and AMYRs, but, in some cases, reduced selectivity between these receptors 18