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Although it is widely observed that ETC functions are compromised in PD, genetic mutations of ETC proteins (either nuclear-encoded or mitochondrial-encoded) are rarely linked to PD

Glutathione is a molecule made of three amino acids: cysteine, glycine, and glutamine

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PI3K, on the other hand, is responsible for the insulin-like actions of the hormones by activating Akt/protein-kinase B (PKB) and protein-kinase C (PKC), which subsequently leads to activation of p70 S6K and glycogen-synthase kinase 3[252]