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By influencing gene expression involved in antioxidant defense and apoptosis regulation, Epithalon may enhance cellular resistance to oxidative damage, a critical factor in the aging process

Two thousand genes with highest variance were used for linear dimensionality reduction (principal component analysis)

Additionally, impaired mitochondria disrupt cellular processes such as apoptosis and autophagy, further contributing to neuronal loss and pathology in these diseases ( 2.3 Oxidative stress Oxidative stress is another important process that occurs in neurodegeneration