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Similarly, HDAC3 also represses genes involved in DNA damage response and cell cycle checkpoints, enabling AML cells to evade genotoxic stress induced by chemotherapy ( In summary, dysregulated histone deacetylation establishes an epigenetic environment conducive to AML progression and therapeutic resistance

Chemosphere 104:155161 Zubair M, Ahmad M, Qureshi Z (2017) Review on arsenic-induced toxicity in male reproductive system and its amelioration

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