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Efficacy and safety of ivacaftor in patients aged 6 to 11 years with cystic fibrosis with a G551D mutation

A similar increase in Ser38 phosphorylation is observed under hypoxic conditions in yeast SOD1 (Thr39 in human SOD1), and is proposed to explain why cellular antioxidant capacity is diminished under hypoxic conditions

DeFronzo RA, Ferrannini E, Groop L, et al

Autophagy is a cellular process responsible for degrading and recycling cellular components, but this process is often impaired in neurodegenerative disorders, leading to failure in clearance of toxic protein aggregates [7]