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Retrieved 28 March 2021

Conclusion: Fazirsiran showed sustained activity and long-term safety in patients with AATD-LD during the OLE phase

Here, overexpression of RABGAP1 by approximately 10-fold was achieved using lentivirus transduction of RABGAP1-mEmerald

Compared with traditional stress models, the LAAA paradigm offers greater reproducibility and allows more precise evaluation of therapeutic interventions [44, 45]