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The phototoxicity of visible light, especially blue light, has been extensively studied

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Conclusion This study established a reliable letrozole-induced PCOS model in Wistar rats, effectively replicating key features of human PCOS, including hormonal imbalances, ovarian dysfunction, and metabolic disturbances

UV exposure induces the production of ROS, which subsequently activate the NF-B and MAPK signaling pathways, leading to increased transcription of pro-inflammatory cytokines (IL-1, TNF-, IL-6 and COX-2) and MMP-1, both of which contribute to inflammation and collagen degradation