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Carotenoids A number of carotenoids such as lycopene, astaxanthin, and other carotenoids have been shown to have neuroprotective properties through upregulation of Nrf2

Both the classes share number of conserved residues in the N-terminal GSH binding domain and possess a distinct structural feature of N-terminal extension (Theodoulou et al., 2003)

Supplementary Movie (download MP4 Non-invasive in vivo fluorescence imaging of ICG 4 -GS-Au25 in PBS-treated and DEM-treated mice

In particular, a prominent regulatory role of protein persulfidation seems apparent, perhaps because sulfide produced by this pathway may react with oxidized thiol groups