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This can result in a slowed metabolic rate and increased fat storage

Pain accompanied by acid reflux symptoms, positional variation (worse when lying down or eased by sitting up), or a prior history of similar, benign episodes also points away from acute cardiac disease

Fatty acid synthase is a metabolic enzyme involved in liponeogenesis and its overexpression has been associated with poor prognosis and shorter disease-free survival in patients with prostate cancer, lung cancer, and sarcoma ( S -palmitoylation of Scrib in epithelial cancer cells (77)