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Overall, BDNF/TrkB signaling is critical for synaptic function and plasticity

As the cartilage that cushions the ends of the bones within joints deteriorates, the body attempts to repair the loss by growing extra bone

Hu Y, Li H, Min J, Yu Y, Liu W, Huang J-W, Zhang L, Yang Y, Dai L, Chen C-C, Guo R-T (2022) Crystal structure and biochemical analysis of the specialized deoxynivalenol-detoxifying glyoxalase SPG from Gossypium hirsutum

Conditions such as diabetes mellitus, multiple sclerosis (MS), and systemic lupus erythematosus have been associated with oxidative stress, potentially exacerbating DED (Lu et al., 2018