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The acquisition of mobile genetic elements carrying mcr genes, which also results in the decorating of lipid A with pEtN, offers a different route toward colistin resistance (Janssen and van Schaik, 2021)

Both conditions may require corticosteroids for acute flares, immunomodulators (azathioprine, 6-mercaptopurine), and biologic therapies (anti-TNF agents, vedolizumab, ustekinumab) for moderate to severe disease

Targeting gut microbiota for the prevention and management of diabetes mellitus by dietary natural products

However, in the absence of a stressor, curcumin can exert pro-oxidant effects when directly applied to cells or mitochondria, leading to apoptosis