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Generalized joint hypermobility: joint hypermobility present in many different joints throughout the body Peripheral joint hypermobility: joint hypermobility limited to the hands and feet Localized joint hypermobility: joint hypermobility in a single joint or group of joints in the same area The Beighton Score is a screening tool for generalized joint hypermobility that measures joint hypermobility on a 9-point scale

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Phase II metabolism then further modifies these metabolites, resulting in the formation of conjugated metabolites that are more water-soluble and suitable for excretion

Prebiotics are defined as a group of substrates that can be selectively utilized by host microorganisms to modulate the gut microbiota, thereby regulating host immunity and cognition via the gut-brain axis (Vulevic et al., 2008)