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As research advances in the future, this mitochondria-targeted drug holds promise to transition from the laboratory to clinical practice, offering new hope for delaying disease progression and improving the quality of life for a wide range of patients

Taylor & Francis, Boca Raton, pp 391399 Dringen R, Kranich O, Hamprecht B (1997) The -glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture

The -KG carrier (encoded by SLC25A11 ) and the dicarboxylate transport mechanisms (dicarboxylate carrier, encoded by SLC25A10 ) are two potential candidates for importing cytosolic GSH to the mitochondria, mainly in the kidney and liver

Tirzepatide for reduction of morbidity and mortality in adults with obesity: rationale and design of the SURMOUNT-MMO trial