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L., Latz, E., Ontiveros, F

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The evidence presented highlights how chronic ethanol consumption contributes to the onset of depressive disorders through various pathways, including the escalation of oxidative stress, the promotion of neuroinflammation, and the dysregulation of neurotrophic factors

Peer-reviewed molecular research has shown that maintaining high levels of cellular NAD+ influences inflammatory pathways through several distinct biological mechanisms: Higher intracellular NAD+ levels directly lower the overall cellular production of IL-1, IL-6, and TNF-