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The duration of effect of fentanyl was defined as the time interval from the time of injection of fentanyl administration to the recovery of righting reflex

NAC-derived cysteine is metabolized by three O 2 -independent enzyme systems: cystathionine -synthase ( CBS) condenses cysteine and homocysteine to generate cystathionine and H 2 S

Conflict of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

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