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This modulatory capacity is crucial for maintaining vascular integrity, regulating platelet function, and mitigating oxidative stress by scavenging free radicals and upregulating antioxidant enzymes, thereby preserving cellular homeostasis and preventing apoptosis

Figure 1 To determine whether cell death follows the pattern of superoxide levels recorded in DPI and MitoQ-treated IMR-5/75 cells, cell toxicity was measured using the CellTox Green Dye that detects modifications in membrane integrity resulting from cell death ( Figures 1A, C )

Most people tolerate B12 supplementation well, even at doses significantly higher than the recommended daily amount

High levels of Hcy can activate the expression and release of inflammatory factors, leading to vascular endothelial dysfunction (Balint et al., 2020)