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Here we have shown that human CBS oligomerises into filaments, adopting (at least) two distinct architectures, respectively, for the basal and activated states

This might be useful in cases where identification of responsible metabolites or types of DNA strand breaks is required, or for antibiotics where in vitro bacterial mutagenicity tests are not feasible

The nave approach of directly predicting aqueous solubility proved superior to predicting intrinsic solubility and converting to aqueous solubility, despite the theoretical advantages of the latter approach