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10.1002/jsfa.11372 J Sci Food Agric

Large scale characterizations of the tumor immune microenvironment (TIME) across multiple cancer types have consistently revealed at least two kinds of immunosuppressive phenotypes.13 In the first category are tumors characterized by abundant infiltration of myeloid derived suppressor cells and regulatory T-cells (T-regs) often present simultaneously with cytotoxic CD8 +lymphocytes, sometimes referred to as immunologically hot tumors

RT-qPCR and immunoblotting showed that while the transcription target of -catenin Glul was significantly higher at both early (2 weeks) and late (6 weeks) time points after oncogene injection (Fig