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Long term metformin therapy and vitamin B12 deficiency: An association to bear in mind PMC If you have been on Metformin for several years, monitoring is essential. The B12 Link: Long term use (typically 4+ years) can interfere with Vitamin B12 absorption. Symptoms to Watch: Fatigue, memory issues Metformin & Vitamin B12 Deficiency: What Diabetics Need to Know TikTok Metformin Affects Vitamin B12 PCOS Nutrition Center

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