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As someone begins to struggle with substance use, you may notice symptoms like: Irritability and mood swings Low energy and lack of motivation Depression, anxiety, and paranoia Withdrawal from hobbies and social circles Changes in behavior, including more risky behavior In some cases, psychotic thoughts have also been reported with GHB addiction

Some research protocols account for this by using comparatively lower dosing ranges in female study cohorts, reflecting a generally increased sensitivity to IGF-1 receptor activation a pattern also documented in broader growth hormone axis research, not unique to IGF-1 LR3 specifically

Minor effects include transient injection site reactions

[5] Broader reviews note that GHK-Cu induces systemic wound healing in rats, mice, and pigs when administered systemically