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Factors That May Affect Appropriateness According to general clinical guidance referenced in published sources, growth hormone secretagogues may not be appropriate for individuals with certain contraindications including active malignancies, uncontrolled diabetes, or other conditions that a clinician would evaluate during the prescribing process

It is the convergence of several adaptive responses, each of which is a normal physiological reaction to weight loss and each of which the GLP-1 medication only partly addresses

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