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Second, although our study quantified OHC loss, we did not perform functional assessments of OHC integrity, such as distortion product otoacoustic emissions (DP-OAEs)

For instance, host-mediated viral clearance due to pre-existing neutralizing antibodies (NAbs) can be mitigated by employing rare serotype recombinants such as 24-RGD-H43m (in Ad5-preexposed populations), polymer shielding, or mesenchymal stem cell (MSC)-based delivery platforms ( From a safety and regulatory standpoint ( Table 7 ), the next 510 years will see the progressive implementation of policies and clinical guidelines