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Treatment of ALF due to WD Patients with ALF due to WD require liver transplantation, which is lifesaving because recovery with medical therapy alone is rare

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C34 and C37 block the Mxra8 attachment by interfering with the stalk region Although multiple pathways contribute to the neutralizing potency of C34 and C37, the obvious differences in neutralizing efficacy observed in pre- and post-attachment experiments imply a possible role of virus attachment blockade for these two antibodies