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The studies analyzed consistently highlight adolescence as a critical period of neurobiological maturationparticularly within the prefrontal cortex and limbic regions that regulate cognition, emotion, and decision-makingduring which nicotine exposure may confer heightened vulnerability ( Nicotine acts on nicotinic acetylcholine receptors, affecting neurotransmission and synaptic plasticity

L., Aucamp, P

Before the study began, a pilot test was conducted with 25 volunteer students to detect difficulties in the execution of the study

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